5 Years.
5 Nephrology Milestones.
1 Mission.

Five years ago, NephU started with a focus on PKD education, evolving into a comprehensive platform for kidney health. Through five transformative years, our mission remains the same: to improve future outcomes for individuals with kidney disease. See how we’ve accomplished this with the help of our community!

Rooted in PKD: NephU’s Founding In 2020⏵

NephU launched in 2020 with a core focus on polycystic kidney disease (PKD), establishing a foundation in rare kidney disease education. Our early work in PKD led to the development of webinars, infographics, and clinical resources that continue to support the nephrology community today. While PKD was our starting point, NephU has since grown to provide resources across the broader spectrum of kidney care, always with the goal of equipping clinicians with practical, high-quality education.

Technology Meets Understanding (Simulators)⏵

In the past five years, NephU created two interactive simulators, one for IgA nephropathy and one for autosomal dominant polycystic kidney disease (ADPKD), providing innovative tools to assist our community with understanding the progression of rare, complex kidney disease. These simulators bridge the gap between theoretical knowledge and practical clinical decision-making—demonstrating how digital tools can enhance medical education and patient care in kidney disease.

Kidney Disease: Improving Global Outcomes (KDIGO) Guidelines For ADPKD⏵

The introduction of KDIGO’s ADPKD guidelines marked a major milestone in nephrology, providing the first global framework for evaluating, monitoring, and managing ADPKD. These evidence-based guidelines help clinicians deliver more consistent, informed, patient-centered care.

A Proliferation-Inducing Ligand (APRIL) In IgA Nephropathy– Break through Treatment For IgA Nephropathy⏵

As part of the tumor necrosis factor (TNF) superfamily, APRIL has emerged as a pivotal factor in the pathogenesis of IgA nephropathy. Its identification has opened the door to targeted, potentially disease-modifying therapies. NephU has developed a range of resources exploring this evolving science and what it could mean for the future of IgA nephropathy care.

Reshaping Kidney Care (Xenotransplantation, SGLT2i, & Genetic Testing)⏵

From breakthroughs like xenotransplantation moving closer to clinical reality, to SGLT2 inhibitors becoming integral to chronic kidney disease management, nephrology has seen a wave of innovation in recent years. Among the most transformative has been the rise of genetic testing, which is redefining how we diagnose, understand, and manage many kidney conditions—opening the door to more precise and personalized approaches.