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Over the past 50 years there has been significant advancement in Polycystic Kidney Disease (PKD) research which has allowed for the translation of these findings into not only an increased awareness of the disease but also improvements in clinical management. During “Polycystic Kidney Disease Research – Past, Present and Future: Part I”, we heard from leading experts, James Calvet, PhD and Arlene Chapman, MD, on the past scientific discoveries and clinical advancements made within the field of PKD research.
With all of these impressive accomplishments, leaders in the field know we must not become complacent but instead push the field even further forward in hopes of greater awareness, more management options, and improved patient outcomes. Join us for Part II of our “Polycystic Kidney Disease Research – Past, Present, and Future” webinar where talented and emerging experts, Vishal Patel, MD & Katharina Hopp, PhD discuss efforts being made to further elucidate the molecular pathways contributing to disease and shed light on cutting edge research that may one day lead to improved options for patients living with PKD.
*Dr Hopp is a paid consultant of Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC). Dr Patel is an unpaid consultant of ODPC. Dr Hajarnis is an employee of OPDC.
University of Colorado, Denver*
Katharina Hopp, PhD is an Assistant Professor of Medicine at the University of Colorado, Denver, where her lab studies the functional role of immune cells on PKD progression. Dr Katharina Hopp obtained her PhD in Biochemistry and Molecular Biology with a focus on Polycystic Kidney Disease (PKD) genetics from the Mayo Clinic, Rochester, Minnesota. She continued her research in PKD as a post-doctoral fellow at the Mayo Clinic Translational PKD Center.
She is the recipient of the Dr Vincent H. Gattone Research Award from the PKD Foundation (2018).
UT Southwestern Medical Center*
Dr Vishal Patel, MD is a Tenured Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He obtained his medical degree from India in 2000 and completed his Internal Medicine residency at Northwestern University (Evanston, IL) in 2004. A stint in a kidney research laboratory at Northwestern sparked his interest in Nephrology. Subsequently, he completed a clinical Nephrology fellowship at UT Southwestern (Dallas, TX) in 2005 and then joined the kidney genetics laboratory of Peter Igarashi, MD, at UT Southwestern as an NIH-funded physician-scientist trainee. His early work involved studying the role of primary cilia in polycystic kidney disease pathogenesis (PKD). In 2009, he started his independent laboratory with a focus on understanding the role of non-coding RNAs in PKD. This work has now evolved to understanding basic RNA biology (translation regulation, RNA chemical modifications, etc.) and developing RNA-based therapeutics approaches for PKD and other kidney genetic disorders. Dr Patel’s lab has been continuously funded by the NIH since 2009, and he receives additional funding from the Department of Defense and the PKD foundation.
Dr Patel is also the Director of a Comprehensive PKD and kidney genetics clinic at UT Southwestern. He serves on the editorial board of Scientific Reports, numerous NIH and DoD grant study sections, is the vice-chair of the scientific advisory committee for the PKD Foundation and has served as a consultant for various pharmaceutical companies. He has mentored many junior scientists, including one who is now a K08-funded Physician-Scientist.
Otsuka Pharmaceutical Development & Commercialization, Inc.*
Sachin Hajarnis, PhD is a Medical Science Liaison at Otsuka Pharmaceuticals. Dr. Hajarnis has a B.S and M.S in Life Sciences from University of Mumbai, India. He obtained a PhD in Biochemistry and Molecular Biology from Colorado State University. Dr. Hajarnis joined the University of Texas Southwestern Medical school in Dallas, as a post-doctoral fellow in the dept of Nephrology where he performed basic research on various aspects of Polycystic Kidney Disease (PKD). He continued his studies on the role of micro-RNAs in PKD as a Research Scientist for several years before joining his current position at Otsuka as a Medical Science Liaison. Dr. Hajarnis has published a book chapter and several original articles in leading journals that include Nature Communications, Proceedings of the National Academy of Sciences, Journal of American Society of Nephrology, American Journal of Physiology- Renal, Journal of Biological Chemistry, to name a few.
Dr. Hajarnis is a member of the American Society of Nephrology (ASN).
NephU is supported by Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC) and Otsuka America Pharmaceutical, Inc. (OAPI) - committed supporters of the Kidney Health Community. The information provided through NephU is intended for the educational benefit of health care professionals and others who support care for those with kidney disease and other related conditions. It is not intended as, nor is it a substitute for, medical care, advice, or professional diagnosis. Health care professionals should use their independent medical judgement when reviewing NephU’s educational resources. Users seeking medical advice should consult with a health care professional. No CME or CEU credits are available through any of the resources provided by NephU. Some of the contributors may be paid consultants of OPDC and/or OAPI.May 2020 MRC2.CORP.X.04767
February 14 from 12:00 pm to 1:00 pm
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