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Mental Health Implications In IgA Nephropathy

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Mental Health Implications In IgA Nephropathy

Background 

Immunoglobulin A nephropathy (IgAN) is a rare, progressive autoimmune kidney disease that leads to chronic inflammation in the kidney. IgAN, a subtype of glomerulonephritis (GN), is induced by the accumulation of IgA-containing immune complexes in the kidney glomeruli that initiate a cascade of inflammatory events, eventually causing irreversible glomerulosclerosis that leads, in many patients, to end stage renal disease (ESRD), reduced quality of life (QoL), a need for dialysis or transplantation, and risk of premature death.1 Those of adolescent age at the time of kidney disease diagnosis showed the highest rate of psychiatric disorders: 33.4 cases per 1,000 person-years compared with other age-groups (children 13.3 and adults 13.2 cases per 1,000 person-years).2   

Did You Know? 

  • IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide, with an incidence of 2.5 per 100,000 population per year.3 
  • The 10-year risk of progression to end stage kidney disease (ESKD) or halving of eGFR is 26%3 
  • Psychiatric disorders were documented in approximately one-eighth of patients with glomerular disease and correlated with clinical disease characteristics such as age, race, proteinuria, and oral medication burden.2 

Why Attend This Webinar? 

  • Join us for this webinar to learn more about mental health in IgAN and how it impacts patients, caregivers, healthcare providers, as well as related stressors.   

What You Will Learn  

  • The importance of mental health as related to IgAN.
  • The impact it has on healthcare providers, patients, and caregivers. 
 

References 

  1. Kwon CS et al. A systematic literature review of the epidemiology, health-related quality of life impact, and economic burden of immunoglobulin a nephropathy. JHEOR. 2021;8(2)36-45. 
  2. Desmond et al. Association between Psychiatric Disorders and Glomerular Disease. Glomerular Dis. 2021;1:118–128. 
  3. Storrar et al. The epidemiology and evolution of IgA nephropathy over two decades: A single centre experience. PLOS ONE. 2022: 1-13. 

Speakers

Kelly Chen

Kelly Chen, NP-BC

Nurse Practitioner, Asian American Engagement Director
Stanford Health Care, IgA Nephropathy Foundation*

Kelly Chen is a patient living with IgA Nephropathy as well as a nephrology nurse practitioner. She first received her education from the University of Pennsylvania’s School of Nursing and Wharton School, studying nursing & healthcare management. From first working as a hospital nurse for a few years then transitioning to healthcare consulting, she leveraged her training in both fields. She then went on to complete her graduate nurse practitioner training also at Penn and served as a frontline worker in a medical ICU during the COVID-19 pandemic in New York City at NYU Langone Health. After the pandemic and with her IgAN diagnosis, she returned to her hometown in the San Francisco Bay Area and decided to pivot to caring for kidney patients like herself, working as an ambulatory nephrology nurse practitioner at Stanford Health Care. For the IgAN Foundation, she currently serves as the Medical & Scientific Advisory Board Member as well as the Asian American Engagement Director.

Sayna Norouzi

Sayna Norouzi, MD

Assistant professor Medicine and clinical nephrologist

Loma Linda University Medical Center*

Dr. Sayna Norouzi is an assistant professor Medicine and clinical nephrologist at Loma Linda university medical center. She completed her fellowship at Baylor College of Medicine in Houston, TX. She is the founder and director of glomerular diseases clinics in Loma Linda. She is also the co-director of online GlomCon Glomerular Diseases fellowship program. She has been selected as the educator of the year for three consecutive years and is a member of Alpha Omega Alpha medical honor society. She is a special interest in glomerular diseases and is involved in multiple research projects and clinical trials.

Hannah Graves

Hannah Graves

Apex Health Innovations, Piedmont Transplant Institute

Hannah Graves is a native of Milwaukee, Wisconsin and graduated with a Bachelor of Arts in Psychology in 2009, followed by a Master’s Degree in Social Work from the University of Wisconsin Milwaukee at the Helen Bader School of Social Welfare. Hannah has significant experience working in hospice, short-term rehab and in dialysis from 201-2019. Currently, Hannah works for Apex Health Innovations, a global healthcare technology company, and Piedmont Transplant Institute, supporting patients through their transplant journey.

Moderators

Marla Dallal

Marla Dallal, PharmD, RPH

Nephrology Senior Medical Science Liaison
Otsuka Pharmaceutical Development & Commercialization, Inc.*

Marla Dallal, PharmD, RPH is a Medical Science Liaison at Otsuka Pharmaceutical Development and Commercialization covering Southern California. She earned her Doctor of Pharmacy degree from the University of Southern California, School of Pharmacy in Los Angeles. While in pharmacy school, Dr Dallal pursued various clinical internships within the acute care and ambulatory care settings at Cedars-Sinai Medical Center and Kaiser Permanente. Prior to joining Otsuka, Dr Dallal held various positions within Medical Affairs at Amgen Inc covering the cardiometabolic and nephrology therapeutic areas. She also served as a preceptor at Amgen Inc, where she instructed pharmacy students on Advanced Pharmacy Practice rotations. She is currently licensed as a pharmacist in the state of California with the National Association Board of Pharmacy.

Jaimini Patel

Jaimini Patel, PharmD, BCCCP

Nephrology Medical Science Liaison

Otsuka Pharmaceutical Development & Commercialization, Inc.*

Jaimini Patel, PharmD, BCCCP, is a Nephrology Medical Science Liaison at Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC). Dr Patel earned her Doctorate in Pharmacy from the University of Michigan, Ann Arbor and completed two years of post-doctoral residency at Beaumont Hospital, Royal Oak and Loyola University Medical Center, respectively, specializing in critical care pharmacy practice. Prior to joining Otsuka, Dr Patel practiced as a critical care pharmacist at the Cleveland Clinic Akron General Medical Center for 3.5 years and has cared for patients in the medical, surgical/trauma, cardiothoracic and neuroscience ICUs, and was significantly involved in the care of patients with COVID-19. Dr Patel holds board certification in critical care pharmacotherapy and is a licensed pharmacist in Michigan, Illinois and Ohio. She is also an active member of the Society of Critical Care Medicine through which she is engaged in research and leadership.

Dr Norouzi, Hannah Graves and Kelly Chen are paid consultants of Otsuka Pharmaceutical Development & Commercialization, Inc.  

Marla Dallal and Jaimini Patel are employees of Otsuka Pharmaceutical Development & Commercialization, Inc.  

Disclaimer: The information provided through NephU is intended for the educational benefit of health care professionals and others who support care for those with kidney disease and other related conditions. It is not intended as, nor is it a substitute for, medical care, advice, or professional diagnosis. Health care professionals should use their independent judgement when reviewing NephU’s educational resources. Users seeking medical advice should consult with a health care professional.

June 2024    US.CORP.X.24.00174

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